Epistasis - Y (wtccc_t2d); I (fastGlu)
Yanyu Liang
March 07, 2018
Read data
source(paste0(root.dir, "scripts/myRLib.R"))
funcset <- readLines(paste0(root.dir, "output-run_step2/fastGlu__wtccc_t2d__wtccc_ctrl/sig_subset.set"))
funcset <- parseFuncSet(funcset)
funcset.names <- names(funcset)
xtyi.files <- strsplit("output-direction_XT_YI/fastGlu__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p1.0000e+00.assoc.logistic:output-direction_XT_YI/fastGlu__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p3.0000e-01.assoc.logistic:output-direction_XT_YI/fastGlu__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p1.0000e-01.assoc.logistic:output-direction_XT_YI/fastGlu__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p3.0000e-02.assoc.logistic:output-direction_XT_YI/fastGlu__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p1.0000e-02.assoc.logistic:output-direction_XT_YI/fastGlu__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p3.0000e-03.assoc.logistic:output-direction_XT_YI/fastGlu__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p1.0000e-03.assoc.logistic:output-direction_XT_YI/fastGlu__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p3.0000e-04.assoc.logistic:output-direction_XT_YI/fastGlu__wtccc_t2d__wtccc_ctrl/xtyi_LDpred_p1.0000e-04.assoc.logistic",
":")[[1]]
ps <- strsplit("1,0.3,0.1,0.03,0.01,0.003,0.001,0.0003,0.0001",
",")[[1]]
inter.files <- strsplit("output-run_step2/fastGlu__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p1.0000e+00.assoc.logistic:output-run_step2/fastGlu__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p3.0000e-01.assoc.logistic:output-run_step2/fastGlu__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p1.0000e-01.assoc.logistic:output-run_step2/fastGlu__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p3.0000e-02.assoc.logistic:output-run_step2/fastGlu__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p1.0000e-02.assoc.logistic:output-run_step2/fastGlu__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p3.0000e-03.assoc.logistic:output-run_step2/fastGlu__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p1.0000e-03.assoc.logistic:output-run_step2/fastGlu__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p3.0000e-04.assoc.logistic:output-run_step2/fastGlu__wtccc_t2d__wtccc_ctrl/interaction.sig_subset_LDpred_p1.0000e-04.assoc.logistic",
":")[[1]]
prs.files <- strsplit("../step1/output-run_step1/fastGlu__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p1.0000e+00.txt:../step1/output-run_step1/fastGlu__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p3.0000e-01.txt:../step1/output-run_step1/fastGlu__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p1.0000e-01.txt:../step1/output-run_step1/fastGlu__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p3.0000e-02.txt:../step1/output-run_step1/fastGlu__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p1.0000e-02.txt:../step1/output-run_step1/fastGlu__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p3.0000e-03.txt:../step1/output-run_step1/fastGlu__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p1.0000e-03.txt:../step1/output-run_step1/fastGlu__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p3.0000e-04.txt:../step1/output-run_step1/fastGlu__wtccc_t2d__wtccc_ctrl/ldpred_LDpred_p1.0000e-04.txt",
":")[[1]]Epistasis
for (i in 1:length(xtyi.files)) {
cat("##", funcset.names[i])
cat("
")
cat("
")
snp.subset <- funcset[[funcset.names[i]]]
# read I ~ SNP
prs <- read.table(paste0(root.dir, prs.files[i]), header = T)
prs$sid <- as.character(prs$sid)
prs.sub <- prs[prs$sid %in% snp.subset, ]
# read others
xtyi <- read.table(paste0(root.dir, xtyi.files[i]), header = T)
xtyi$SNP <- as.character(xtyi$SNP)
yt.xtyi <- xtyi[(xtyi$SNP %in% snp.subset) & (xtyi$SNP %in%
prs.sub$sid), ]
yt.xtyi.xt <- yt.xtyi[yt.xtyi$TEST == "ADD", ]
yt.xtyi.yi <- yt.xtyi[yt.xtyi$TEST == "PRS", ]
inter <- read.table(paste0(root.dir, inter.files[i]), header = T)
inter$SNP <- as.character(inter$SNP)
inter <- inter[inter$TEST == "ADDxPRS", ]
yt.inter <- inter[(inter$SNP %in% snp.subset) & (inter$SNP %in%
prs.sub$sid), ]
# order all rows
yt.xtyi.xt <- yt.xtyi.xt[order(yt.xtyi.xt$SNP), ]
yt.xtyi.yi <- yt.xtyi.yi[order(yt.xtyi.yi$SNP), ]
yt.inter <- yt.inter[order(yt.inter$SNP), ]
prs.sub <- prs.sub[order(prs.sub$sid), ]
# check direction
prs.sub$nt1 <- as.character(prs.sub$nt1)
yt.xtyi.xt$A1 <- as.character(yt.xtyi.xt$A1)
yt.inter$A1 <- as.character(yt.inter$A1)
if (sum(prs.sub$nt1 != yt.xtyi.xt$A1) != 0 | sum(prs.sub$nt1 !=
yt.inter$A1) != 0) {
print("Direction does not match. Exit!")
quit()
}
yt.xtyi.xt.mean.std <- getMeanStd(yt.xtyi.xt$SNP, yt.xtyi.xt$P,
yt.xtyi.xt$OR, "Y~Gi+I (Gi)")
yt.xtyi.yi.mean.std <- getMeanStd(yt.xtyi.yi$SNP, yt.xtyi.yi$P,
yt.xtyi.yi$OR, "Y~Gi+I (I)")
yt.inter.mean.std <- getMeanStd(yt.inter$SNP, yt.inter$P,
yt.inter$OR, "Y~Gi*I")
prs.sub.mean.std <- data.frame(SNP = prs.sub$sid, Mean = prs.sub$ldpred_beta,
Std = 0, Type = "I~Gi")
# create data frame for plot
df <- rbind(yt.xtyi.xt.mean.std, yt.xtyi.yi.mean.std, prs.sub.mean.std,
yt.inter.mean.std)
ratio <- max(1, nrow(yt.inter)/40)
cat
p <- ggplot(df) + geom_point(aes(x = SNP, y = Mean)) + geom_errorbar(aes(x = SNP,
ymin = Mean - 1.96 * Std, ymax = Mean + 1.96 * Std),
colour = "black", width = 0.1) + geom_hline(yintercept = 0,
color = "red") + facet_grid(. ~ Type, scales = "free_x") +
coord_flip() + theme(axis.text.x = element_text(angle = 90,
hjust = 1))
p2 <- ggplot(yt.inter) + geom_bar(aes(x = SNP, y = -log10(P)),
stat = "identity") + coord_flip() + ggtitle("Interaction P-value")
subchunkify(p, ratio)
subchunkify(p2, ratio)
cat("
")
inter.plus.gwas.pval <- cbind(yt.inter, yt.xtyi.xt$P)
colnames(inter.plus.gwas.pval) <- c(colnames(yt.inter), "GWAS.P")
pander(inter.plus.gwas.pval[order(inter.plus.gwas.pval$P,
decreasing = F), ])
cat("
")
cat("
")
}p1.0000e+00
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 1.299 | 2.47 | 0.01351 | 3.105e-05 |
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.7721 | -2.225 | 0.02611 | 2.621e-05 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 1.214 | 1.827 | 0.06764 | 3.892e-05 |
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 1.245 | 1.617 | 0.1058 | 4.322e-05 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 0.8509 | -1.495 | 0.135 | 5.136e-06 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 1.152 | 1.367 | 0.1716 | 5.551e-08 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 0.8724 | -1.224 | 0.221 | 4.114e-10 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 1.128 | 1.174 | 0.2403 | 5.669e-05 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 0.8865 | -1.106 | 0.2686 | 3.839e-12 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 1.117 | 1.035 | 0.3009 | 1.447e-05 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 1.108 | 1.012 | 0.3114 | 1.009e-05 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 0.9058 | -0.9099 | 0.3629 | 5.308e-12 |
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 1.095 | 0.8948 | 0.3709 | 1.202e-05 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 1.095 | 0.8812 | 0.3782 | 1.313e-07 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 0.9198 | -0.8226 | 0.4108 | 1.679e-10 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 1.086 | 0.7393 | 0.4597 | 6.588e-06 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 1.071 | 0.6805 | 0.4962 | 4.398e-06 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 0.939 | -0.6127 | 0.5401 | 8.773e-11 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 0.9375 | -0.6076 | 0.5434 | 2.482e-05 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 1.064 | 0.5983 | 0.5497 | 5.588e-06 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 0.9031 | -0.5951 | 0.5518 | 6.198e-06 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 0.9398 | -0.5905 | 0.5548 | 8.688e-05 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 0.9398 | -0.5905 | 0.5548 | 8.688e-05 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 0.9423 | -0.5606 | 0.5751 | 1.717e-05 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 0.9496 | -0.4989 | 0.6178 | 6.382e-12 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 0.9405 | -0.4735 | 0.6358 | 1.113e-05 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 1.041 | 0.3843 | 0.7007 | 6.257e-06 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 1.082 | 0.3541 | 0.7232 | 3.509e-05 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 0.9577 | -0.3444 | 0.7306 | 4.618e-06 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 0.974 | -0.2559 | 0.798 | 2.002e-05 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 0.9713 | -0.2512 | 0.8017 | 9.313e-06 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 0.973 | -0.2193 | 0.8265 | 7.445e-06 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 0.9734 | -0.2164 | 0.8286 | 1.325e-05 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 0.9729 | -0.2136 | 0.8309 | 3.414e-06 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 0.9813 | -0.1829 | 0.8549 | 2.723e-08 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 1.019 | 0.1821 | 0.8555 | 2.162e-05 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 1.032 | 0.1704 | 0.8647 | 5.643e-06 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 0.9818 | -0.1496 | 0.8811 | 2.007e-05 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 0.9852 | -0.1461 | 0.8839 | 2.303e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 0.9852 | -0.1461 | 0.8839 | 2.303e-07 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 0.9823 | -0.1439 | 0.8856 | 1.352e-05 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 0.9858 | -0.1388 | 0.8896 | 3.108e-08 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 0.9884 | -0.1132 | 0.9099 | 2.154e-10 |
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 0.9906 | -0.09154 | 0.9271 | 1.536e-05 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 1.009 | 0.0903 | 0.928 | 2.084e-05 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 0.9913 | -0.07045 | 0.9438 | 1.329e-05 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 1.007 | 0.06992 | 0.9443 | 5.71e-05 |
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 0.9929 | -0.06179 | 0.9507 | 1.318e-05 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 1.006 | 0.05776 | 0.9539 | 3.934e-05 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 1.006 | 0.05767 | 0.954 | 1.53e-10 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 0.9954 | -0.04489 | 0.9642 | 1.171e-06 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.9953 | -0.03952 | 0.9685 | 3.989e-05 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 1.001 | 0.006971 | 0.9944 | 3.193e-07 |
p3.0000e-01
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 1.28 | 2.468 | 0.01359 | 3.126e-05 |
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.7666 | -2.423 | 0.0154 | 2.686e-05 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 1.209 | 1.888 | 0.05899 | 3.9e-05 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 0.8461 | -1.641 | 0.1008 | 5.183e-06 |
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 1.227 | 1.595 | 0.1107 | 4.417e-05 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 1.137 | 1.321 | 0.1864 | 8.275e-08 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 0.8879 | -1.132 | 0.2576 | 8.308e-10 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 0.8916 | -1.121 | 0.2623 | 8.571e-12 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 1.118 | 1.1 | 0.2714 | 1.332e-05 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 1.092 | 0.9118 | 0.3619 | 5.681e-05 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 0.9115 | -0.9077 | 0.3641 | 1.225e-11 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 1.09 | 0.8843 | 0.3765 | 1.89e-07 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 0.9258 | -0.8074 | 0.4194 | 3.283e-10 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 1.079 | 0.7887 | 0.4303 | 4.552e-06 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 0.9296 | -0.7296 | 0.4656 | 2.518e-05 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 1.072 | 0.7252 | 0.4683 | 1.049e-05 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 0.9326 | -0.6985 | 0.4848 | 1.732e-05 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 1.076 | 0.6937 | 0.4879 | 6.339e-06 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 1.063 | 0.6238 | 0.5327 | 5.193e-06 |
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 1.059 | 0.5985 | 0.5495 | 1.248e-05 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 0.9484 | -0.5501 | 0.5823 | 1.712e-10 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 1.089 | 0.503 | 0.615 | 6.965e-06 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 0.9224 | -0.4971 | 0.6191 | 6.069e-06 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 0.942 | -0.4885 | 0.6252 | 1.037e-05 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 0.9549 | -0.4761 | 0.634 | 1.125e-06 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 0.9561 | -0.4636 | 0.6429 | 2.214e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 0.9561 | -0.4636 | 0.6429 | 2.214e-07 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 0.9577 | -0.4381 | 0.6613 | 0.0001094 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 0.9577 | -0.4381 | 0.6613 | 0.0001094 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 0.9622 | -0.3923 | 0.6949 | 2.762e-08 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 1.036 | 0.3659 | 0.7144 | 2.186e-05 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 0.9672 | -0.3392 | 0.7345 | 3.14e-08 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 0.9691 | -0.3246 | 0.7455 | 3.104e-07 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 0.9712 | -0.3004 | 0.7639 | 1.323e-11 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 1.029 | 0.3002 | 0.764 | 2.097e-05 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 1.03 | 0.2935 | 0.7692 | 5.467e-06 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 0.9681 | -0.273 | 0.7849 | 6.12e-06 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 1.027 | 0.2719 | 0.7857 | 3.967e-05 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.9706 | -0.2653 | 0.7908 | 4.127e-05 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 0.9716 | -0.2636 | 0.7921 | 9.84e-06 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 0.9722 | -0.2408 | 0.8097 | 1.254e-05 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 0.9722 | -0.2405 | 0.8099 | 7.095e-06 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 0.9739 | -0.2182 | 0.8273 | 3.213e-06 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 1.021 | 0.2176 | 0.8277 | 3.018e-10 |
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 1.017 | 0.1747 | 0.8613 | 1.529e-05 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 0.9806 | -0.167 | 0.8674 | 1.282e-05 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 1.029 | 0.1374 | 0.8907 | 3.737e-05 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 0.987 | -0.1302 | 0.8964 | 5.648e-05 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 0.9859 | -0.1229 | 0.9022 | 1.908e-05 |
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 0.991 | -0.08292 | 0.9339 | 1.43e-05 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 1.008 | 0.08186 | 0.9348 | 4.288e-10 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 1.002 | 0.01932 | 0.9846 | 1.734e-05 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 1 | 0.001923 | 0.9985 | 1.991e-05 |
p1.0000e-01
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.8009 | -2.508 | 0.01214 | 2.872e-05 |
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 1.188 | 2.136 | 0.03269 | 3.287e-05 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 0.8681 | -1.717 | 0.08598 | 5.338e-06 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 1.143 | 1.641 | 0.1008 | 4.083e-05 |
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 1.146 | 1.307 | 0.1913 | 4.528e-05 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 1.11 | 1.28 | 0.2007 | 1.117e-05 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 1.095 | 1.16 | 0.2459 | 1.274e-07 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 0.919 | -1.025 | 0.3054 | 1.963e-11 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 0.9252 | -0.9903 | 0.322 | 1.1e-06 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 0.9267 | -0.8981 | 0.3691 | 1.752e-09 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 1.127 | 0.881 | 0.3783 | 1.021e-05 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 0.9349 | -0.8515 | 0.3945 | 2.218e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 0.9349 | -0.8515 | 0.3945 | 2.218e-07 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 0.9343 | -0.8264 | 0.4086 | 2.917e-11 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 1.065 | 0.8052 | 0.4207 | 2.79e-07 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 0.9386 | -0.7745 | 0.4386 | 2.711e-05 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 0.9389 | -0.7715 | 0.4404 | 1.85e-05 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 1.063 | 0.7712 | 0.4406 | 4.425e-06 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 0.9424 | -0.752 | 0.452 | 3.157e-07 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 0.9459 | -0.7188 | 0.4723 | 6.463e-10 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 1.056 | 0.6914 | 0.4893 | 5.031e-06 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 1.046 | 0.5795 | 0.5623 | 2.192e-05 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 1.045 | 0.5643 | 0.5725 | 2.081e-05 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 0.956 | -0.5623 | 0.5739 | 2.93e-08 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.951 | -0.5548 | 0.579 | 4.478e-05 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 1.043 | 0.5371 | 0.5912 | 3.978e-05 |
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 1.041 | 0.5099 | 0.6101 | 1.49e-05 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 0.9506 | -0.5085 | 0.6111 | 9.336e-06 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 0.9605 | -0.5034 | 0.6147 | 3.311e-08 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 1.042 | 0.4874 | 0.626 | 5.721e-06 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 0.9657 | -0.4493 | 0.6532 | 3.387e-10 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 1.031 | 0.388 | 0.698 | 5.367e-05 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 1.029 | 0.3726 | 0.7094 | 6.081e-10 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 1.027 | 0.3324 | 0.7396 | 1.932e-05 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 0.9595 | -0.3137 | 0.7537 | 5.834e-06 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 0.9722 | -0.296 | 0.7672 | 1.133e-05 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 1.023 | 0.293 | 0.7696 | 8.745e-10 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 0.9728 | -0.2901 | 0.7717 | 6.342e-06 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 0.9767 | -0.2882 | 0.7732 | 5.258e-05 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 0.9744 | -0.2617 | 0.7936 | 2.889e-06 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 0.975 | -0.2615 | 0.7937 | 7.876e-06 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 0.9601 | -0.2473 | 0.8047 | 3.911e-05 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 0.9786 | -0.2279 | 0.8197 | 1.155e-05 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 1.018 | 0.2236 | 0.823 | 1.05e-05 |
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 0.9817 | -0.2119 | 0.8322 | 1.662e-05 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 0.9844 | -0.1767 | 0.8598 | 1.09e-05 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 0.9869 | -0.1653 | 0.8687 | 0.0001345 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 0.9869 | -0.1653 | 0.8687 | 0.0001345 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 0.9896 | -0.1116 | 0.9112 | 1.73e-05 |
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 1.008 | 0.09958 | 0.9207 | 1.253e-05 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 1.005 | 0.05208 | 0.9585 | 2.185e-05 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 0.998 | -0.0253 | 0.9798 | 2.723e-11 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 0.9988 | -0.01534 | 0.9878 | 5.22e-06 |
p3.0000e-02
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.8583 | -2.291 | 0.02196 | 2.902e-05 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 0.9026 | -1.648 | 0.09931 | 5.58e-06 |
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 1.095 | 1.485 | 0.1376 | 3.435e-05 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 1.089 | 1.392 | 0.1641 | 9.576e-06 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 0.9321 | -1.19 | 0.234 | 1.154e-06 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 1.071 | 1.114 | 0.2654 | 4.279e-05 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 1.108 | 0.9988 | 0.3179 | 1.295e-05 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 0.9437 | -0.9679 | 0.3331 | 2.425e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 0.9437 | -0.9679 | 0.3331 | 2.425e-07 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 1.057 | 0.9195 | 0.3578 | 3.851e-06 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 0.9468 | -0.9143 | 0.3606 | 3.468e-07 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 1.053 | 0.8728 | 0.3828 | 1.264e-07 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 0.9489 | -0.845 | 0.3981 | 1.665e-11 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 1.049 | 0.8099 | 0.418 | 1.987e-05 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 0.951 | -0.7991 | 0.4242 | 2.049e-05 |
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 1.048 | 0.7839 | 0.4331 | 1.396e-05 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 1.047 | 0.7794 | 0.4357 | 3.843e-05 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 1.046 | 0.7742 | 0.4388 | 2.112e-05 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 0.9526 | -0.7719 | 0.4402 | 3.015e-05 |
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 1.062 | 0.7667 | 0.4433 | 4.432e-05 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 0.9577 | -0.6969 | 0.4859 | 2.474e-11 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.955 | -0.674 | 0.5003 | 4.85e-05 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 0.9602 | -0.6345 | 0.5257 | 1.582e-09 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 1.037 | 0.6194 | 0.5357 | 1.803e-05 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 1.037 | 0.6192 | 0.5358 | 2.743e-07 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 0.9689 | -0.5362 | 0.5918 | 5.366e-10 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 0.9366 | -0.5342 | 0.5932 | 3.94e-05 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 0.9703 | -0.4994 | 0.6175 | 3.178e-08 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 1.028 | 0.4692 | 0.6389 | 5.039e-10 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 0.9673 | -0.438 | 0.6614 | 8.588e-06 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 1.026 | 0.4368 | 0.6623 | 7.315e-10 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 0.9741 | -0.4332 | 0.6649 | 3.579e-08 |
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 0.975 | -0.3871 | 0.6987 | 1.803e-05 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 0.9807 | -0.3229 | 0.7468 | 5.988e-06 |
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 0.9815 | -0.3164 | 0.7517 | 1.148e-05 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 1.019 | 0.3068 | 0.759 | 5.831e-06 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 0.9786 | -0.2985 | 0.7653 | 1.019e-05 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 0.9827 | -0.2956 | 0.7675 | 2.791e-10 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 0.9809 | -0.2655 | 0.7906 | 5.573e-06 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 0.9838 | -0.2615 | 0.7937 | 4.748e-05 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 0.9805 | -0.2597 | 0.7951 | 2.617e-06 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 0.9828 | -0.2395 | 0.8107 | 1.033e-05 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 1.013 | 0.2161 | 0.8289 | 2.134e-11 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 0.9875 | -0.2131 | 0.8312 | 9.59e-06 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 1.012 | 0.1944 | 0.8458 | 5.166e-06 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 0.986 | -0.1919 | 0.8478 | 6.516e-06 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 1.011 | 0.1744 | 0.8616 | 0.0001107 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 1.011 | 0.1744 | 0.8616 | 0.0001107 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 0.9904 | -0.1638 | 0.8699 | 5.006e-05 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 1.007 | 0.1025 | 0.9183 | 1.813e-05 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 0.9953 | -0.0657 | 0.9476 | 1.56e-05 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 0.9942 | -0.05858 | 0.9533 | 5.741e-06 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 0.9975 | -0.03722 | 0.9703 | 1.156e-05 |
p1.0000e-02
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.8847 | -1.956 | 0.0505 | 2.762e-05 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 0.9109 | -1.607 | 0.1081 | 5.83e-06 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 1.071 | 1.193 | 0.2327 | 8.978e-06 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 0.9406 | -1.11 | 0.267 | 1.231e-06 |
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 1.065 | 1.109 | 0.2672 | 3.329e-05 |
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 1.064 | 1.109 | 0.2676 | 1.299e-05 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 1.061 | 1.073 | 0.2831 | 1.855e-05 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 1.058 | 1.028 | 0.304 | 3.598e-05 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 1.057 | 1.013 | 0.311 | 1.972e-05 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 1.054 | 0.954 | 0.3401 | 1.673e-05 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 0.9474 | -0.9091 | 0.3633 | 2.142e-05 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 1.052 | 0.8854 | 0.3759 | 4.17e-05 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 0.9498 | -0.8656 | 0.3867 | 3.153e-05 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 1.085 | 0.8503 | 0.3952 | 1.321e-05 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 0.9523 | -0.8404 | 0.4007 | 1.1e-11 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 1.048 | 0.8279 | 0.4077 | 3.604e-06 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 0.9573 | -0.7776 | 0.4368 | 2.622e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 0.9573 | -0.7776 | 0.4368 | 2.622e-07 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 0.9584 | -0.7587 | 0.448 | 3.742e-07 |
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 0.9604 | -0.7243 | 0.4689 | 1.058e-05 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.9554 | -0.7142 | 0.4751 | 5.009e-05 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 0.9593 | -0.7141 | 0.4752 | 1.608e-11 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 0.9655 | -0.632 | 0.5274 | 8.816e-06 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 0.9662 | -0.5733 | 0.5665 | 1.148e-09 |
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 0.9663 | -0.5599 | 0.5755 | 1.785e-05 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 0.9404 | -0.5332 | 0.5939 | 4.097e-05 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 0.9692 | -0.5323 | 0.5945 | 4.439e-05 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 0.9718 | -0.514 | 0.6072 | 3.674e-10 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 1.026 | 0.4698 | 0.6385 | 1.123e-07 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 0.9743 | -0.4689 | 0.6392 | 5.024e-05 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 1.024 | 0.4257 | 0.6704 | 3.408e-10 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 0.9764 | -0.4199 | 0.6745 | 6.625e-06 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 1.024 | 0.4161 | 0.6773 | 4.97e-10 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 1.023 | 0.3949 | 0.6929 | 8.376e-05 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 1.023 | 0.3949 | 0.6929 | 8.376e-05 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 1.02 | 0.3581 | 0.7203 | 2.46e-07 |
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 1.025 | 0.3365 | 0.7365 | 4.277e-05 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 0.982 | -0.326 | 0.7444 | 1.893e-10 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 0.9843 | -0.2813 | 0.7785 | 3.319e-08 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 1.012 | 0.2168 | 0.8284 | 1.366e-11 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 0.9883 | -0.2082 | 0.8351 | 3.745e-08 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 1.014 | 0.2018 | 0.8401 | 1.452e-05 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 1.012 | 0.172 | 0.8634 | 1.393e-05 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 0.9888 | -0.1568 | 0.8754 | 8.226e-06 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 0.9935 | -0.1153 | 0.9082 | 6.43e-06 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 1.006 | 0.09994 | 0.9204 | 1.151e-05 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 0.9965 | -0.05056 | 0.9597 | 4.923e-06 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 0.9968 | -0.04741 | 0.9622 | 9.461e-06 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 0.9968 | -0.04506 | 0.9641 | 2.472e-06 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 1.003 | 0.03702 | 0.9705 | 5.647e-06 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 1.002 | 0.02798 | 0.9777 | 5.108e-06 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 1.001 | 0.0211 | 0.9832 | 4.905e-06 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 1.001 | 0.01025 | 0.9918 | 9.562e-06 |
p3.0000e-03
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.9016 | -1.518 | 0.1289 | 2.552e-05 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 0.9094 | -1.51 | 0.1311 | 6.051e-06 |
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 1.094 | 1.485 | 0.1376 | 1.202e-05 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 1.085 | 1.346 | 0.1783 | 1.547e-05 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 1.083 | 1.343 | 0.1792 | 1.718e-05 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 1.079 | 1.28 | 0.2007 | 3.329e-05 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 1.078 | 1.272 | 0.2034 | 1.821e-05 |
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 0.93 | -1.193 | 0.2328 | 9.736e-06 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 0.9312 | -1.117 | 0.264 | 4.234e-05 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 0.9354 | -1.1 | 0.2713 | 8.102e-06 |
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 1.062 | 0.9776 | 0.3283 | 3.119e-05 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 0.9411 | -0.9652 | 0.3345 | 6.845e-12 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 1.062 | 0.9605 | 0.3368 | 3.914e-05 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 0.9398 | -0.9584 | 0.3379 | 2.15e-05 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 0.9457 | -0.9304 | 0.3521 | 1.289e-06 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 0.9422 | -0.9172 | 0.359 | 3.162e-05 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 0.9486 | -0.8367 | 0.4028 | 9.821e-12 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 1.077 | 0.7066 | 0.4798 | 1.292e-05 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 0.9586 | -0.6909 | 0.4896 | 5.059e-05 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.9535 | -0.6895 | 0.4905 | 5.025e-05 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 0.9584 | -0.6575 | 0.5108 | 7.903e-10 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 1.041 | 0.6473 | 0.5174 | 8.833e-06 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 1.047 | 0.6273 | 0.5305 | 1.381e-05 |
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 0.9603 | -0.6105 | 0.5415 | 1.709e-05 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 0.9664 | -0.5636 | 0.573 | 2.439e-10 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 1.031 | 0.5034 | 0.6147 | 6.315e-05 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 1.031 | 0.5034 | 0.6147 | 6.315e-05 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 1.037 | 0.4828 | 0.6292 | 4.817e-06 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 1.03 | 0.4786 | 0.6322 | 3.519e-06 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 0.9725 | -0.4592 | 0.6461 | 3.917e-07 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 0.9725 | -0.4574 | 0.6474 | 1.239e-10 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 0.9734 | -0.4432 | 0.6576 | 2.752e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 0.9734 | -0.4432 | 0.6576 | 2.752e-07 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 1.034 | 0.4414 | 0.6589 | 9.081e-06 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 1.029 | 0.38 | 0.7039 | 8.999e-06 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 0.9772 | -0.376 | 0.7069 | 6.852e-06 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 0.9565 | -0.3511 | 0.7255 | 4.326e-05 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 1.026 | 0.3324 | 0.7396 | 2.406e-06 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 1.02 | 0.3277 | 0.7432 | 3.256e-10 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 1.019 | 0.3034 | 0.7616 | 2.224e-10 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 1.018 | 0.2637 | 0.792 | 1.127e-05 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 1.02 | 0.2522 | 0.8009 | 8.046e-06 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 0.9858 | -0.2307 | 0.8175 | 7.13e-06 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 1.016 | 0.2169 | 0.8282 | 1.077e-05 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 0.9874 | -0.1252 | 0.9003 | 5.503e-06 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 1.007 | 0.09666 | 0.923 | 3.74e-06 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 1.004 | 0.05971 | 0.9524 | 8.425e-12 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 1.003 | 0.05569 | 0.9556 | 2.194e-07 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 1.002 | 0.04062 | 0.9676 | 3.772e-08 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 0.9977 | -0.03895 | 0.9689 | 9.853e-08 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 1.002 | 0.03649 | 0.9709 | 4.824e-06 |
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 1.002 | 0.023 | 0.9816 | 4.133e-05 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 0.9988 | -0.01957 | 0.9844 | 3.321e-08 |
p1.0000e-03
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 1.116 | 1.611 | 0.1072 | 1.141e-05 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 0.8985 | -1.5 | 0.1336 | 4.145e-05 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 1.107 | 1.492 | 0.1357 | 1.47e-05 |
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 0.9033 | -1.484 | 0.1378 | 9.255e-06 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 1.098 | 1.399 | 0.1618 | 1.634e-05 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 0.9094 | -1.388 | 0.1653 | 7.703e-06 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 0.9081 | -1.365 | 0.1723 | 6.193e-06 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 1.094 | 1.342 | 0.1796 | 3.167e-05 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 1.092 | 1.328 | 0.1841 | 1.729e-05 |
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.9153 | -1.156 | 0.2477 | 2.415e-05 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 1.079 | 1.092 | 0.2748 | 3.795e-05 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 1.087 | 1.006 | 0.3142 | 1.357e-05 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 0.9323 | -0.9946 | 0.3199 | 4.678e-12 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 0.9325 | -0.9612 | 0.3365 | 2.146e-05 |
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 1.067 | 0.9453 | 0.3445 | 3.047e-05 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 0.9345 | -0.9291 | 0.3529 | 3.151e-05 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 0.9398 | -0.88 | 0.3788 | 6.637e-12 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 1.076 | 0.8691 | 0.3848 | 4.713e-06 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 1.104 | 0.8412 | 0.4002 | 1.269e-05 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 0.9441 | -0.8301 | 0.4065 | 5.1e-05 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 1.072 | 0.8283 | 0.4075 | 8.917e-06 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 0.9479 | -0.7944 | 0.427 | 1.329e-06 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 1.066 | 0.761 | 0.4467 | 8.842e-06 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 0.9479 | -0.7433 | 0.4573 | 5.703e-10 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.9496 | -0.6673 | 0.5046 | 5.042e-05 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 1.06 | 0.6553 | 0.5123 | 2.401e-06 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 0.959 | -0.6164 | 0.5377 | 1.761e-10 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 1.051 | 0.5587 | 0.5763 | 8.022e-06 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 0.9664 | -0.5006 | 0.6167 | 8.825e-11 |
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 0.9636 | -0.4977 | 0.6187 | 1.647e-05 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 1.031 | 0.4444 | 0.6567 | 4.981e-05 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 1.031 | 0.4444 | 0.6567 | 4.981e-05 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 0.9708 | -0.4368 | 0.6622 | 8.575e-08 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 0.9706 | -0.4342 | 0.6642 | 7.059e-06 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 1.025 | 0.3208 | 0.7483 | 1.108e-05 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 0.9666 | -0.3016 | 0.7629 | 5.344e-06 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 1.018 | 0.267 | 0.7894 | 2.322e-10 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 1.017 | 0.2415 | 0.8091 | 7.544e-06 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 1.016 | 0.2355 | 0.8139 | 1.582e-10 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 0.985 | -0.2236 | 0.823 | 1.938e-07 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 0.9854 | -0.2165 | 0.8286 | 4.024e-07 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 1.013 | 0.1964 | 0.8443 | 3.501e-06 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 1.013 | 0.1907 | 0.8488 | 3.748e-08 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 1.013 | 0.1873 | 0.8514 | 8.832e-06 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 0.9877 | -0.1807 | 0.8566 | 2.836e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 0.9877 | -0.1807 | 0.8566 | 2.836e-07 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 1.014 | 0.1695 | 0.8654 | 8.82e-06 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 1.011 | 0.1563 | 0.8758 | 3.281e-08 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 1.01 | 0.1351 | 0.8926 | 4.748e-06 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 1.01 | 0.122 | 0.9029 | 3.032e-06 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 0.9831 | -0.1185 | 0.9057 | 4.47e-05 |
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 0.9914 | -0.09712 | 0.9226 | 4.029e-05 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 0.9979 | -0.03096 | 0.9753 | 5.784e-12 |
p3.0000e-04
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 0.8801 | -1.667 | 0.09546 | 8.944e-06 |
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 1.135 | 1.66 | 0.09687 | 1.107e-05 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 0.8771 | -1.645 | 0.09998 | 4.171e-05 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 1.127 | 1.574 | 0.1155 | 1.429e-05 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 0.8866 | -1.573 | 0.1158 | 7.446e-06 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 1.107 | 1.361 | 0.1736 | 1.599e-05 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 0.8987 | -1.346 | 0.1782 | 6.305e-06 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 1.103 | 1.32 | 0.187 | 3.098e-05 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 1.101 | 1.294 | 0.1957 | 1.689e-05 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 1.105 | 1.276 | 0.2018 | 3.742e-05 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 1.119 | 1.207 | 0.2276 | 1.329e-05 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 1.166 | 1.166 | 0.2437 | 1.264e-05 |
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.9111 | -1.092 | 0.2748 | 2.285e-05 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 1.107 | 1.071 | 0.2844 | 4.617e-06 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 1.104 | 1.036 | 0.3001 | 8.741e-06 |
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 1.079 | 0.9873 | 0.3235 | 3.041e-05 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 1.096 | 0.9632 | 0.3355 | 8.665e-06 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 0.9265 | -0.9433 | 0.3455 | 2.157e-05 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 0.9299 | -0.8965 | 0.37 | 3.167e-05 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 0.9328 | -0.895 | 0.3708 | 5.198e-05 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 1.088 | 0.8474 | 0.3968 | 2.364e-06 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 0.9374 | -0.8214 | 0.4114 | 4.154e-12 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 0.945 | -0.7436 | 0.4571 | 7.841e-08 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 0.9458 | -0.7409 | 0.4587 | 1.356e-06 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 1.074 | 0.7214 | 0.4707 | 7.881e-06 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 0.9454 | -0.7132 | 0.4757 | 5.889e-12 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 1.054 | 0.6797 | 0.4967 | 7.713e-06 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 0.9493 | -0.6515 | 0.5147 | 5.084e-10 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.9491 | -0.601 | 0.5478 | 5.102e-05 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 0.959 | -0.551 | 0.5817 | 1.534e-10 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 1.038 | 0.4756 | 0.6343 | 4.118e-05 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 1.038 | 0.4756 | 0.6343 | 4.118e-05 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 0.9657 | -0.4591 | 0.6461 | 1.774e-07 |
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 0.9648 | -0.4326 | 0.6653 | 1.602e-05 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 0.971 | -0.3858 | 0.6997 | 7.68e-11 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 0.971 | -0.3776 | 0.7057 | 8.855e-06 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 1.035 | 0.3684 | 0.7126 | 2.64e-06 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 0.9737 | -0.3492 | 0.7269 | 7.162e-06 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 1.033 | 0.3483 | 0.7276 | 7.728e-06 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 1.026 | 0.3323 | 0.7397 | 2.028e-10 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 1.022 | 0.2915 | 0.7707 | 1.381e-10 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 0.9641 | -0.2902 | 0.7716 | 5.192e-06 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 1.041 | 0.2466 | 0.8053 | 4.633e-05 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 1.018 | 0.2381 | 0.8118 | 3.715e-08 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 1.017 | 0.2182 | 0.8273 | 3.248e-08 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 1.017 | 0.2099 | 0.8337 | 4.719e-06 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 0.9853 | -0.1944 | 0.8458 | 3.512e-06 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 1.015 | 0.1795 | 0.8576 | 1.086e-05 |
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 0.9891 | -0.1105 | 0.912 | 3.989e-05 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 0.9929 | -0.09425 | 0.9249 | 4.081e-07 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 0.9951 | -0.06445 | 0.9486 | 2.883e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 0.9951 | -0.06445 | 0.9486 | 2.883e-07 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 1.004 | 0.05485 | 0.9563 | 5.085e-12 |
p1.0000e-04
| CHR | SNP | BP | A1 | TEST | NMISS | OR | STAT | P | GWAS.P | |
|---|---|---|---|---|---|---|---|---|---|---|
| 78 | 10 | rs9422545 | 0 | A | ADDxPRS | 4862 | 0.866 | -1.759 | 0.0785 | 8.78e-06 |
| 75 | 10 | rs9326506 | 0 | A | ADDxPRS | 4862 | 0.8723 | -1.673 | 0.09431 | 7.311e-06 |
| 72 | 9 | rs10817674 | 0 | A | ADDxPRS | 4862 | 0.8684 | -1.653 | 0.09828 | 4.202e-05 |
| 132 | 12 | rs7132840 | 0 | T | ADDxPRS | 4862 | 1.144 | 1.649 | 0.09924 | 1.082e-05 |
| 129 | 12 | rs11178531 | 0 | A | ADDxPRS | 4862 | 1.138 | 1.588 | 0.1122 | 1.397e-05 |
| 69 | 6 | rs10806665 | 0 | A | ADDxPRS | 4862 | 1.219 | 1.402 | 0.1608 | 1.27e-05 |
| 138 | 12 | rs10506626 | 0 | A | ADDxPRS | 4862 | 1.11 | 1.312 | 0.1894 | 1.571e-05 |
| 165 | 15 | rs2930291 | 0 | A | ADDxPRS | 4862 | 0.8951 | -1.301 | 0.1934 | 6.33e-06 |
| 144 | 12 | rs11178648 | 0 | T | ADDxPRS | 4862 | 1.107 | 1.281 | 0.2001 | 3.046e-05 |
| 87 | 10 | rs7923866 | 0 | T | ADDxPRS | 4862 | 1.112 | 1.262 | 0.2071 | 3.706e-05 |
| 141 | 12 | rs2270584 | 0 | A | ADDxPRS | 4862 | 1.105 | 1.258 | 0.2084 | 1.657e-05 |
| 9 | 2 | rs12692592 | 0 | G | ADDxPRS | 4862 | 1.134 | 1.253 | 0.2102 | 1.319e-05 |
| 27 | 2 | rs11693602 | 0 | C | ADDxPRS | 4862 | 1.117 | 1.086 | 0.2776 | 4.573e-06 |
| 15 | 2 | rs7593730 | 0 | T | ADDxPRS | 4862 | 1.115 | 1.064 | 0.2873 | 8.653e-06 |
| 177 | 16 | rs11075123 | 0 | A | ADDxPRS | 4862 | 0.9106 | -1.034 | 0.3012 | 2.194e-05 |
| 12 | 2 | rs4077463 | 0 | A | ADDxPRS | 4862 | 1.107 | 0.996 | 0.3192 | 8.58e-06 |
| 33 | 2 | rs11688935 | 0 | G | ADDxPRS | 4862 | 0.923 | -0.9303 | 0.3522 | 2.203e-05 |
| 90 | 10 | rs7917983 | 0 | C | ADDxPRS | 4862 | 0.9269 | -0.9297 | 0.3525 | 7.62e-08 |
| 45 | 3 | rs440646 | 0 | G | ADDxPRS | 4862 | 0.9279 | -0.8989 | 0.3687 | 5.313e-05 |
| 39 | 2 | rs17248501 | 0 | C | ADDxPRS | 4862 | 1.077 | 0.8897 | 0.3736 | 7.597e-06 |
| 81 | 10 | rs5015480 | 0 | T | ADDxPRS | 4862 | 1.074 | 0.8671 | 0.3859 | 3.048e-05 |
| 36 | 2 | rs10931347 | 0 | A | ADDxPRS | 4862 | 0.9281 | -0.8641 | 0.3875 | 3.238e-05 |
| 24 | 2 | rs6718526 | 0 | T | ADDxPRS | 4862 | 1.095 | 0.8518 | 0.3943 | 2.33e-06 |
| 150 | 12 | rs7972188 | 0 | C | ADDxPRS | 4862 | 0.9402 | -0.7381 | 0.4605 | 8.911e-06 |
| 204 | 16 | rs9930506 | 0 | G | ADDxPRS | 4862 | 0.9435 | -0.7223 | 0.4701 | 1.374e-06 |
| 30 | 2 | rs10929982 | 0 | C | ADDxPRS | 4862 | 1.078 | 0.7044 | 0.4812 | 7.735e-06 |
| 51 | 6 | rs10946398 | 0 | C | ADDxPRS | 4862 | 1.056 | 0.6569 | 0.5112 | 3.789e-05 |
| 57 | 6 | rs9460546 | 0 | G | ADDxPRS | 4862 | 1.056 | 0.6569 | 0.5112 | 3.789e-05 |
| 6 | 1 | rs6691406 | 0 | A | ADDxPRS | 4862 | 0.9408 | -0.6524 | 0.5141 | 5.172e-05 |
| 99 | 10 | rs7901695 | 0 | C | ADDxPRS | 4862 | 0.9468 | -0.6479 | 0.517 | 4.333e-12 |
| 48 | 3 | rs3846119 | 0 | T | ADDxPRS | 4862 | 1.117 | 0.6383 | 0.5233 | 4.773e-05 |
| 93 | 10 | rs7901275 | 0 | C | ADDxPRS | 4862 | 0.9503 | -0.6244 | 0.5323 | 1.719e-07 |
| 60 | 6 | rs9465871 | 0 | C | ADDxPRS | 4862 | 1.059 | 0.5738 | 0.5661 | 2.525e-06 |
| 105 | 10 | rs4132670 | 0 | A | ADDxPRS | 4862 | 0.9548 | -0.5489 | 0.5831 | 6.163e-12 |
| 111 | 10 | rs12243326 | 0 | C | ADDxPRS | 4862 | 0.9558 | -0.5314 | 0.5951 | 5.193e-10 |
| 153 | 12 | rs1510937 | 0 | C | ADDxPRS | 4862 | 0.9604 | -0.4955 | 0.6203 | 3.541e-06 |
| 63 | 6 | rs7767391 | 0 | C | ADDxPRS | 4862 | 1.05 | 0.487 | 0.6263 | 7.421e-06 |
| 120 | 10 | rs10885409 | 0 | C | ADDxPRS | 4862 | 1.037 | 0.4449 | 0.6564 | 2.005e-10 |
| 96 | 10 | rs4074720 | 0 | T | ADDxPRS | 4862 | 0.9679 | -0.4019 | 0.6878 | 1.507e-10 |
| 174 | 16 | rs2099106 | 0 | T | ADDxPRS | 4862 | 0.9651 | -0.401 | 0.6884 | 1.559e-05 |
| 123 | 10 | rs11196208 | 0 | C | ADDxPRS | 4862 | 1.033 | 0.4003 | 0.6889 | 1.363e-10 |
| 159 | 12 | rs7961581 | 0 | C | ADDxPRS | 4862 | 1.032 | 0.3655 | 0.7148 | 4.685e-06 |
| 189 | 16 | rs17817288 | 0 | A | ADDxPRS | 4862 | 0.9755 | -0.3049 | 0.7605 | 7.222e-06 |
| 3 | 1 | rs4655595 | 0 | G | ADDxPRS | 4862 | 0.9626 | -0.2819 | 0.778 | 5.05e-06 |
| 195 | 16 | rs7193144 | 0 | C | ADDxPRS | 4862 | 1.019 | 0.2326 | 0.8161 | 3.701e-08 |
| 108 | 10 | rs10787472 | 0 | C | ADDxPRS | 4862 | 0.9824 | -0.2176 | 0.8277 | 7.542e-11 |
| 198 | 16 | rs8050136 | 0 | A | ADDxPRS | 4862 | 1.017 | 0.2086 | 0.8347 | 3.236e-08 |
| 114 | 10 | rs7077039 | 0 | C | ADDxPRS | 4862 | 1.017 | 0.2021 | 0.8398 | 5.112e-12 |
| 162 | 14 | rs8012854 | 0 | G | ADDxPRS | 4862 | 0.9866 | -0.1278 | 0.8983 | 3.976e-05 |
| 168 | 15 | rs2903265 | 0 | A | ADDxPRS | 4862 | 0.9902 | -0.108 | 0.914 | 1.058e-05 |
| 192 | 16 | rs1121980 | 0 | A | ADDxPRS | 4862 | 0.994 | -0.07421 | 0.9408 | 4.109e-07 |
| 180 | 16 | rs9939973 | 0 | A | ADDxPRS | 4862 | 0.9953 | -0.05807 | 0.9537 | 2.906e-07 |
| 183 | 16 | rs9940128 | 0 | A | ADDxPRS | 4862 | 0.9953 | -0.05807 | 0.9537 | 2.906e-07 |